Day 1
|
7:45 – 8:30 |
Breakfast and Registration |
8:30 – 8:50 |
Opening Remarks
Prof. Jimmy Hsia, University of Illinois at Urbana-Champaign
Prof. Roger Kamm, Massachusetts Institute of Technology
Dr. Clark Cooper, Program Director, CMMI, NSF
Dr. Adnan Akay, Division Director, CMMI, NSF |
Session I: Current State of the Knowledge
Chair: Prof. Muhammad Zaman, University of Texas at Austin |
8:50 – 9:10 |
Prof. Michael Sheetz, Columbia University
Much on Parts and Cells But Little on Meso-scale Functions |
9:10 – 9:30 |
Prof. Mary Boyce, MIT
Mechanics of Cell Deformations: Constitutive Modeling of the Finite Deformation Behavior of Biological Networks and Membranes |
9:30 – 9:50 |
Prof. Paul Janmey, University of Pennsylvania
Cell type-specific responses to substrate rigidity |
9:50 – 10:10 |
Prof. Metin Sitti, Carnegie Mellon University
Cell and Bacteria Actuated Microobjects |
10:10 – 10:30 |
Prof. Jean Schwarzbauer, Princeton University
Development of tissue mimetics based on natural extracellular matrices |
10:30 – 10:50 |
Coffee Break |
Session II: Critical Issues and Challenges
Chair: Prof. Chwee Teck Lim, National University of Singapore |
10:50 – 11:10 |
Prof. Dennis Discher, University of Pennsylvania
Is Matricellular Elasticity felt by cells both in vitro & in vivo? |
11:10 – 11:30 |
Prof. Beth Pruitt, Stanford University
Critical Issues and Challenges of Engineering Tissues from Cells |
11:30 – 11:50 |
Prof. Ravi Iyengar, Mt. Sinai School of Medicine
Regulatory Networks Controlling Cell State Decisions |
11:50 – 12:10 |
Prof. Huajian Gao, Brown University
Nanomechanics of biological systems – from single molecular bonds to continuum mechanics descriptions of cell adhesion |
12:10 – 12:30 |
Prof. Clare Waterman, NIH/NHLBI
Animation of macromolecular ensembles: How do protein dynamics translate into higher order cellular properties? |
12:30 – 1:30 |
Lunch |
1:30 – 1:35 |
Introduction to Participants on Brainstorming Session 1 |
1:40 – 2:40 |
Brainstorming Session 1: Critical Issues and Challenges
Group 1 (Room 555)
| Leaders: | Prof. Taher Saif, University of Illinois |
| | Prof. Denis Wirtz, Johns Hopkins University |
Group 2 (Room 525)
| Leaders: | Prof. Gang Bao, Georgia Inst. of Technology |
| | Prof. Richard Murray, California Inst. of Technology |
Group 3 (Room 535)
| Leaders: | Prof. Victor Barocas, University of Minnesota |
| | Prof. Dan Hammer, University of Pennsylvania |
Group 4 (Room 545)
| Leaders: | Prof. Phil LeDuc, Carnegie Mellon University |
| | Prof. Sasha Popel, Johns Hopkins University |
Four breakout groups, each led by two co-chairs, will have in-depth discussion on the issues of 1) where the opportunities are; 2) how to identify the critical problems; 3) what the grand challenges and obstacles are; etc. |
2:40 – 3:20 |
Reporting from Brainstorming Session 1 |
3:20 – 3:40 |
Coffee Break |
Session III: General Discussion on Critical Issues
| Moderators: | Prof. Ellen Arruda, University of Michigan |
| | Prof. Dan Fletcher, UC-Berkeley | |
3:40 – 4:10 |
Two moderators will be invited to conduct this session to further focus on the goals of the workshop, i.e., the critical issues facing the cell biology and engineering communities in this area. The objective of this session is to bring the critical issues and grand challenges raised by workshop participants to a sharper focus. |
Session IV: Tools and Resources
Chair: Prof. Michelle Oyen, Cambridge University |
4:10 – 4:30 |
Prof. Roger Kamm, MIT
Multi-Scale and Multi-Physics Computational Tools |
4:30 – 4:50 |
Prof. Jay Groves, UC-Berkeley
Membrane mechanics and cellular signal transduction |
4:50 – 5:10 |
Prof. G. Ravichandran, California Institute of Technology
Quantitative Characterization of 3-D Deformation in Soft BioMaterials and its Application to Cell Mechanics |
5:10 – 5:30 |
Prof. Sam Safran, Weizmann Institute of Science, Isreal
Structure and function of biological cells: theoretical approaches from soft matter physics |
5:30 – 5:50 |
Prof. Harry Asada, MIT
A Stochastic Approach to Dynamic Modeling and Control of Collective Cell Behavior |
6:30 – 7:00 |
Cash Bar |
7:00 – 9:30 |
Dinner
Dinner Presentation
Professor Subra Suresh, Dean of Engineering, MIT
Perspectives on Research at the Intersections of Engineering, Life Sciences, and Medicine |
Day 2
|
8:00 – 8:30 |
Breakfast |
8:30 – 9:00 |
Government Perspectives
Dr. Richard Buckius, Assistant Director for Engineering, NSF
NSF, Engineering and Interdisciplinary Research |
9:00 – 10:00 |
Brainstorming Session 2: Opportunities in Collaborative Research between Mechanics, Controls, Systems Engineering and Cell Biology
Four breakout groups, each led by two co-chairs, will have in-depth discussion on opportunities in collaborative research. The groups will focus on collaborations between mechanics and biology, control theory and biology, system engineering and biology, respectively. The groups will also discuss the impacts of such collaborative research, and potentials to bring about transformation in the way engineering and cell biology research is done. |
10:00 – 10:15 |
Coffee Break |
10:15 – 10:45 |
Reporting from the Brainstorming Session 2 |
10:45 – 11:45 |
Brainstorming Session 3: Resources Needed, Format of Collaboration, and Recommendations
Four breakout groups, each led by two co-chairs, will brainstorm to identify the preferred format for collaboration, the most effective way to nurture such collaboration, and the educational needs. |
11:45 – 1:00 |
Lunch |
1:00 – 1:30 |
Reporting from the Brainstorming Session 3 |
1:30 – 2:00 |
General Discussion on the Recommendations of the Workshop |
2:00 – 2:30 |
Concluding Remarks from NSF and Other Funding Agency Representatives |
2:30 – 4:30 |
Special Session for Organizers, Group Leaders: Preparation of a coherent document containing workshop findings and recommendations. This document will be used by NSF PDs and other federal funding agencies to define the future funding policies in this area. |
4:30 |
Adjourn |
